Vitamin K is an essential cofactor in the hepatic synthesis of prothrombin and other blood clotting factors. Phytomenadione is a naturally occurring vitamin K. It is the only vitamin K compound used to reverse hypoprothrombinaemia and haemorrhage caused by anticoagulant overdose (e.g. rat bait poisoning).
Indications
Warfarin-type and second generation hydroxycoumarin anticoagulant poisoning in cats and dogs.
Contraindications
Do not administer to pregnant animals.
Administration
Administration should only be done after consulting your veterinarian.
Tablets may be used five to seven days at the rate of 1-12.5mg/kg, according to severity of the condition, clinical response and changing clotting times. Tablets may be crumbled and added to foods.
Evaluate prothrombin levels at least every three days for nine to ten days. If prolongation of clotting time remains, reinstitute therapy for another one to two weeks. Poisoning by second generation hydroxycoumarins (brodifacoum, bromadiolone) may require K-Mav therapy for three to four weeks.
